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Donald A Mahler Selected Research

Dyspnea (Shortness of Breath)

1/2021High-Flow Nasal Cannula Therapy for Exertional Dyspnea in Patients with Cancer: A Pilot Randomized Clinical Trial.
1/2020Enhanced Drug and Device Development by Targeting "Relief of Dyspnea".
10/2019The Impact of Twice-Daily Indacaterol/Glycopyrrolate on the Components of Health-Related Quality of Life and Dyspnea in Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease.
1/2018Results of a Pulmonologist Survey Regarding Knowledge and Practices With Inhalation Devices for COPD.
9/2016Efficacy of Indacaterol/Glycopyrronium in Patients with COPD Who Have Increased Dyspnea with Daily Activities.
11/2015FLIGHT1 and FLIGHT2: Efficacy and Safety of QVA149 (Indacaterol/Glycopyrrolate) versus Its Monocomponents and Placebo in Patients with Chronic Obstructive Pulmonary Disease.
8/2015Indacaterol vs tiotropium in COPD patients classified as GOLD A and B.
1/2015Recent advances in dyspnea.
6/2014Antagonism of substance P and perception of breathlessness in patients with chronic obstructive pulmonary disease.
6/2013Efficacy and safety of indacaterol and tiotropium in COPD patients according to dyspnoea severity.
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Donald A Mahler Research Topics

Disease

53Chronic Obstructive Pulmonary Disease (COPD)
07/2022 - 10/2002
29Dyspnea (Shortness of Breath)
01/2021 - 12/2002
3Hypoxia (Hypoxemia)
01/2021 - 05/2007
3Pneumonia (Pneumonitis)
01/2015 - 05/2013
2Obstructive Lung Diseases (Obstructive Lung Disease)
11/2015 - 06/2014
2Heart Diseases (Heart Disease)
05/2010 - 03/2010
1Neoplasms (Cancer)
01/2021
1Human Influenza (Influenza)
06/2014
1Asthma (Bronchial Asthma)
12/2012
1Inflammation (Inflammations)
12/2012
1Cough
09/2012
1Pain (Aches)
06/2011
1Muscle Weakness
06/2008
1Hyperoxia
01/2007
1Hypercapnia
01/2007

Drug/Important Bio-Agent (IBA)

19Bronchodilator Agents (Bronchodilators)IBA
01/2021 - 12/2002
11indacaterolIBA
10/2019 - 07/2010
9Muscarinic AntagonistsIBA
10/2019 - 06/2014
9Tiotropium Bromide (Spiriva)FDA Link
10/2019 - 11/2003
8Opioid Analgesics (Opioids)IBA
01/2015 - 03/2010
7Oxygen (Dioxygen)IBA
01/2021 - 01/2007
7Adrenal Cortex Hormones (Corticosteroids)IBA
01/2019 - 10/2002
6Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric
10/2019 - 06/2014
5Salmeterol Xinafoate (Serevent)FDA Link
09/2016 - 10/2002
4Pharmaceutical PreparationsIBA
01/2020 - 01/2016
4GoldIBA
09/2016 - 01/2015
4EndorphinsIBA
05/2013 - 06/2011
3PowdersIBA
10/2019 - 04/2014
3Fluticasone (Cutivate)FDA LinkGeneric
09/2016 - 10/2002
3indacaterol-glycopyrronium combinationIBA
11/2015 - 06/2014
3fluticasone furoateFDA Link
01/2015 - 05/2013
3Naloxone (Narcan)FDA LinkGeneric
01/2015 - 06/2011
3Opioid Receptors (Opioid Receptor)IBA
01/2015 - 04/2013
3vilanterolIBA
01/2015 - 05/2013
3Fluticasone-Salmeterol Drug Combination (Advair)FDA Link
11/2014 - 09/2006
3Saline SolutionIBA
06/2011 - 04/2005
2Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2019
2revefenacinIBA
10/2019 - 01/2019
2Formoterol Fumarate (Oxis)FDA Link
12/2014 - 06/2010
2Morphine (MS Contin)FDA LinkGeneric
04/2013 - 06/2011
1Indicators and Reagents (Reagents)IBA
01/2022
1tiotropium-olodaterolIBA
01/2021
1Fibrinogen (Factor I)FDA Link
01/2021
1Cholinergic Agents (Cholinergics)IBA
01/2019
1Clostridium perfringens epsilon-toxinIBA
09/2016
1tartaric acid (tartrate)FDA Link
12/2014
1Substance PIBA
06/2014
1Aprepitant (Emend)FDA Link
06/2014
1GSK573719IBA
06/2014
1NeuropeptidesIBA
06/2014
1Adrenocorticotropic Hormone (ACTH)FDA Link
05/2013
1Ketoconazole (Nizoral)FDA LinkGeneric
05/2013
1Anti-Inflammatory Agents (Anti-Inflammatories)IBA
12/2012
1Lactic Acid (Lactate)FDA LinkGeneric
08/2011
1Oxyhemoglobins (Oxyhemoglobin)IBA
08/2011
1Furosemide (Lasix)FDA LinkGeneric
06/2011
1Narcotic Antagonists (Opioid Antagonists)IBA
06/2011
1Peptides (Polypeptides)IBA
06/2011
1Carbon DioxideIBA
01/2007
1prednylidene (Pred)IBA
04/2005
1SolutionsIBA
04/2005
1Ipratropium Drug Combination AlbuterolFDA Link
04/2005
1BromidesIBA
04/2005
1Interleukin-8 (Interleukin 8)IBA
09/2004
1ChemokinesIBA
09/2004
1Monoclonal AntibodiesIBA
09/2004
1InterleukinsIBA
09/2004
1Immunoglobulin G (IgG)IBA
09/2004
1Albuterol (Salbutamol)FDA LinkGeneric
12/2002
1pyrachlostrobin (F 500)IBA
10/2002

Therapy/Procedure

22Therapeutics
01/2021 - 12/2002
7Nebulizers and Vaporizers (Inhaler)
07/2022 - 04/2014
6Dry Powder Inhalers
10/2019 - 06/2013
5Activities of Daily Living (ADL)
08/2012 - 03/2005
3Drug Therapy (Chemotherapy)
11/2020 - 12/2002
2Respiratory Therapy (Therapy, Respiratory)
01/2020 - 01/2018
2Metered Dose Inhalers (Metered Dose Inhaler)
01/2018 - 01/2018
2Terminal Care (Care, Terminal)
05/2010 - 03/2010
1Cannula
01/2021
1Denervation
12/2019
1Patient Readmission
07/2017
1Intravenous Administration
06/2011
1Positive-Pressure Respiration (Positive End-Expiratory Pressure)
05/2010
1Noninvasive Ventilation
05/2007
1Self Administration (Administration, Self)
01/2004